Your whole genome holds the answers to more than just living in space.

Source: www.flickr.com/photos/nasacommons * U.S. only. Requires doctor order.

$999 whole genome sequencing to improve
your health and longevity.


The first genome took 13 years and $2.7 billion to complete. Today, thanks to our new, innovative sequencing techniques, we can offer Veritas myGenome whole genome sequencing at a much more reasonable cost. So, billions of people can now get access to their unique genetic information without having to spend billions of dollars to do it. Supplies limited to 5,000 in 2016.

Live in the know. Today. And tomorrow.


By sequencing your entire genome, you’ll not only be able to utilize what you learn about your health today, but also long into the future. For years to come, you can refer to your genetic sequencing to stay on top of any health issues you may have or are concerned about having. Parents will know what inherited genetics they may pass on to their children. And, someday soon, we predict we’ll all be carrying full genome cards and using them to select our food, personal care products, and fitness routines. Whether it’s today or in the future, you don’t have to guess about the best ways to maximize your health. With Veritas’ cutting-edge whole genome sequencing, you will always live in the know.

You. And your genes.


Your genes are not your fate.

Yes, our genes tell us who we are. But they don’t have to dictate who we’re going to be. Sequencing your whole genome gives you a unique and detailed playbook to help you manage your health like never before. Following this playbook, along with new medical discoveries, as well as understanding how your genes interact with other aspects of your health and environment, can give you a greater opportunity to make real life changes and live a longer, healthier life.

More personalized and comprehensive approach to your health.

Your whole genome sequence will give you insights into a variety of health conditions and lifestyle traits that may affect how you and your doctor monitor your health, tailor annual exams, and decide on monitoring frequency. Simply put, when you know your particular risk of a health condition, you are in a much better position to be proactive and benefit from a more personalized and comprehensive approach than following the typical ‘one size fits all’ protocol. Your whole genome sequence makes you an equal partner in your doctor’s care for you. For example, someone who discovers they’re a BRCA carrier as part of their whole genome sequence, but who otherwise would not have been considered high risk because of their ethnicity or family history, is in a better position regarding observation, monitoring, and perhaps better outcome. And, being healthy is not all about disease. Knowing lifestyle traits such as athletic, metabolic, and nutritional genetic preferences may point to lifestyle changes that could improve your health and quality of life. Two examples are the approach to exercise (e.g. decide long distance versus interval training) and food choices they eat (e.g. manage iron intake with an elevated risk of hemochromatosis). You could say that whole genome sequencing is about more personalized, ongoing, whole health based on your genetic make-up.

Insights for a lifetime.

Your whole genome sequence is as much about today as it is about your lasting health. Since your genome does not change, when scientific discoveries and their clinical relevance is validated, you can access more useful information to help you take the best possible care of your health on an ongoing basis. For example, while we evaluate pharmacogenomics (adverse drug reactions) when we initially sequence your whole genome, as more drugs come to market and their pharmacogenomic profiles are known and demonstrated, your records can be updated with additional interpretation of the already stored whole genome sequence. The truth is that we’re only at the very beginning of understanding the full, lasting value of your whole genome sequence.

myGenome is about more than learning what makes you you.
It’s about learning what can make you a healthier you.

Veritas myGenome uses the most advanced whole genome sequencing to give you insights into your health risks for almost all clinical conditions that could be attributable to genetic defects and variants. Interpretation of your results covers the 56 genes recommended by the American College of Medical Genetics (ACMG) as well as 10 additional and different groups of hereditary health conditions plus five groups of personal traits.

ABDS 56

ACMG 56

In this group, we examine 56 genes that are recommended by the American College of Medical Genetics (ACMG) to look for highly pathogenic germline mutations. We report 32 genetic conditions that are caused by those monogenic mutations. Risk assessments of diseases such as hypertrophic cardiomyopathy, familial hypercholesterolemia, and familial medullary thyroid cancer are included in the report. The ACMG encourages ordering physicians and laboratories to report the constitutional (germline) mutations found in the 56 genes regardless of the indication for which the clinical sequencing was ordered.13

Show More Information →
DISEASE LIST (24)
  • Hereditary Breast and ovarian cancer
  • Li-Fraumeni Syndrome
  • Peutz-Jeghers Syndrome
  • Lynch Syndrome
  • Familial adenomatous polyposis
  • MYH-Associated Polyposis; Adenomas, multiple colorectal, FAP type 2; Colorectal adenomatous polyposis, autosomal recessive, with pilomatricomas
  • Von Hippel Lindau syndrome
  • Multiple endocrine Neoplasia Type 1
  • Multiple endocrine Neoplasia Type 2
  • Familial Medullary Thyroid Cancer (FMTC)
  • PTEN Hamartoma Tumor Syndrome
  • Retinoblastoma
  • Hereditary Paraganglioma-Pheochromocytoma Syndrome
  • Tuberous Sclerosis Complex
  • WT1-related Wilms tumor
  • Neurofibromatosis type 2
  • EDS - vascular type
  • Marfan Syndrome, Loeys-Dietz Syndromes, and Familial Thoracic Aortic Aneurysms and Dissections
  • Hypertrophic cardiomyopathy, Dilated cardiomyopathy
  • Catecholaminergic polymorphic ventricular tachycardia
  • Arrhythmogenic right ventricular cardiomyopathy
  • Romano-Ward Long QT Syndromes Types 1, 2, and 3, Brugada Syndrome
  • Familial hypercholesterolemia
  • Malignant hyperthermia susceptibility
GENE LIST (56)

ACTA2, ACTC1, APC, APOB, BRCA1, BRCA2, CACNA1S, COL3A1, DSC2, DSG2, DSP, FBN1, GLA, KCNH2, KCNQ1, LDLR, LMNA, MEN1, MLH1, MSH2, MSH6, MUTYH, MYBPC3, MYH11, MYH7, MYL2, MYL3, MYLK, NF2, PCSK9, PKP2, PMS2, PRKAG2, PTEN, RB1, RET, RYR1, RYR2, SCN5A, SDHAF2, SDHB, SDHC, SDHD, SMAD3, STK11, TGFBR1, TGFBR2, TMEM43, TNNI3, TNNT2, TP53, TPM1, TSC1, TSC2, VHL, WT1

Cancer

Cancer

Cancers develop when genetic mutations trigger uncontrolled cell growth. In roughly 10% of cancers, the mutations are inherited from parents and can be passed to children. People who carry these mutations are at an increased risk of developing these diseases, but early detection and medical intervention can prevent further spread and improve a patient's prognosis. This category investigates more than 150 of the most frequent cancer genes for 20 different disease categories, including breast cancer, prostate cancer, colon cancer, etc.

Show More Information →
DISEASE LIST (20)
  • Breast cancer
  • Colon cancer
  • Intestine cancer
  • Kidney cancer
  • Liver cancer
  • Neuro/endocrine cancer
  • Ovarian cancer
  • Pancreatic cancer
  • Skin cancer
  • Stomach cancer
  • Bladder & urinary tract cancer
  • Uterus cancer
  • Testicular germ cell cancer
  • Prostate cancer
  • Eye cancer
  • Blood cancer
  • Sarcoma
  • Thyroid cancer
  • Familial non-Hodgkin lymphoma
  • Head and neck cancer
GENE LIST (150+)

AIP, AKT1, AKT2, ALK, APC, AR, ATM, AXIN2, BAP1, BARD1, BLM, BMPR1A, BRAF, BRCA1, BRCA2, BRIP1, BTNL2, BUB1B, CASP10, CBL, CDB8, CDC73, CDH1, CDK4, CDKN1B, CDKN1C, CDKN2A, CDKNA2, CHEK2, CREBBP, DDR2, DICER1, EGFR, ELAC2, EP300, EPCAM, ERBB2, EXT2, FAH, FBLN1, FGFR1, FGFR3, FH, FLCN, FOXP1, FUS, GATA2, GFI1, GNAQ, GPC3, GREM1, HER2, HNF1A, HNF1B, HOXB13, HRAS, JAK2, KAT6B, KIT, KRAS, LHX4, LITAF, LKB1, MAP2K1, MAP3K6, MAX, MC1R, MEK1, MEN1, MET, MITF, MLH1, MLH3, MRE11A, MSH2, MSH6, MSR1, MTAP, MUTYH, MXI1, MYH11, NBN, NF1, NF2, NRAS, NSD1, NTRK1, PALB2, PALLD, PAX3, PDGFRA, PDGFRB, PHOX2B, PIK3CA, PMS2, POLD1, POLE, PPARG, PRDM16, PRKAR1A, PRKCSH, PRSS1, PTCH1, PTEN, PTPN11, RAD50, RAD51C, RAD51D, RAF1, RASA1, RB1, RBBP8, RET, RHBDF2, RIT1, RNASEL, ROS1, RPS17, RPS19, RPS24, RUNX1, SDHA, SDHAF2, SDHB, SDHC, SDHD, SETBP1, SMAD4, SMARCA4, SMARCB1, SOS1, SPINK1, SQSTM1, STIL, STK11, SUFU, TCF7L2, TERT, TGFBR2, TMEM127, TP53, TP63, TPM3, TSC1, TSC2, UMOD, VHL, WRN, WT1, XRCC2, ZFHX3

Cardio

Cardiovascular Diseases

Cardiovascular diseases have remained the No.1 cause of death.14 Cardiovascular diseases are frequently portrayed as "silent killers" for the general population but could be prevented through early intervention if genetic factors are identified and monitored. This grouping investigates over 240 disease-associated genes to explore health conditions involving heart and circulatory system, including 10 well-known cardiovascular diseases as well as conditions manifested in other genetic syndromes; for example, arrhythmia, hyperlipoproteinemia, hypertension, coronary artery disease, etc.

Show More Information →
DISEASE LIST (10)
  • Arrhythmia
  • Hyperlipoproteinemia
  • Cardiomyopathy
  • Thoracic aortic aneurysm and disection
  • Pulmonary hypertension
  • Hypertension
  • Atrial fibrillation
  • Left ventricular non-compaction
  • Coronary artery disease
  • Atrial septal defect
GENE LIST (240+)

ABCA1, ABCC6, ABCC9, ABCG5, ABCG8, ACTA2, ACTC1, ACTN2, ACVRL1, AGT, AKAP9, ANGPTL3, ANK2, ANKRD1, APOA1, APOA5, APOB, APOC2, APOC3, APOE, BAG3, BCOR, BMPR2, BOLA3, BRAF, C3, CACNA1C, CACNA2D1, CACNB2, CALM1, CASQ, CASQ2, CAV1, CAV3, CBL, CBS, CD36, CETP, CHD7, CHRM2, COL3A1, COL5A1, COL5A2, CPS1, CRYAB, CSPR3, CSRP3, CUL3, DES, DMD, DOLK, DSC2, DSCG2, DSG2, DSP, DTNA, EHMT1, ELN, EMD, ENG, EVC, EVC2, EYA4, FBN1, FBN2, FHL2, FKTN, FLNA, FOXC1, FOXF1, FRAS1, FREM2, FXN, G6PC3, GAA, GATA4, GATA6, GATAD1, GDF2, GJA1, GJA5, GLA, GPD1, GPD1L, GPIHBP1, GREM2, GRIP1, HCN4, HRAS, ILK, JAG1, JPH2, JUP, KCNA5, KCND3, KCNE1, KCNE2, KCNE3, KCNE4, KCNE5, KCNH2, KCNJ2, KCNJ5, KCNJ8, KCNQ1, KIF1B, KLHL3, KRAS, LAMA4, LAMP2, LCAT, LDB3, LDLR, LDLRAP1, LIPA, LIPC, LMF1, LMN, LMNA, LPL, MAP2K1, MAP2K2, MED12, MEK1, MID1, MKKS, MMP3, MTND1, MTND5, MTND6, MTTD, MTTG, MTTH, MTTI, MTTK, MTTL1, MTTL2, MTTM, MTTP, MTTQ, MTTS1, MTTS2, MURC, MYBPC3, MYH11, MYH6, MYH7, MYL2, MYL3, MYLK, MYLK2, MYOM1, MYOZ2, MYPN, NEBL, NEXN, NKX2-5, NODAL, NOTCH1, NOTCH2, NPPA, NR3C2, NRAS, NUP155, PCSK9, PDLIM3, PIGL, PKP2, PLN, PLOD1, PPARG, PRDM16, PRKAG2, PRKG1, PTPN11, RAB23, RAF1, RANGRF, RASA1, RBM20, RET, RIT1, RYR2, SAR1B, SARS2, SCARB1, SCN1B, SCN2B, SCN3B, SCN4B, SCN5A, SDHA, SDHB, SDHD, SGCD, SHOC2, SKI, SLC19A2, SLC2A10, SMAD3, SMAD4, SMAD9, SNTA1, SOS1, SPRED1, TAZ, TBX1, TBX5, TCAP, TERT, TGFB2, TGFB3, TGFBR1, TGFBR2, TMEM127, TMEM43, TMPO, TNNC1, TNNI3, TNNT2, TPM1, TRDN, TRPM4, TTN, TTR, TXNRD2, VCL, WNK1, WNK4, WT1, rs3903239/ upstream to PRRX1, rs3807989 /intronic to CAV1, rs10821415 / intronic to C9orf3, rs10824026 /upstream to SYNPO2L, rs1152591/intronic to SYNE2, rs7164883/intronic to HCN4, rs2200733/ downstream to PITX2, rs10033464/ downsream to PITX2, rs17042171/downstream to PITX2, rs2106261/intronic to ZFHX3, rs13376333/intronic to KCNN3

Immuno

Immune disorders

The immune system is our body's natural defense system, playing a role in keeping out foreign invaders like viruses, bacteria, and pollen. A deficient immune system severely decreases our ability to fight infection and can be life-threatening. On the other hand, an overactive immune system such as seen in auto-immune conditions attacks healthy cells of the body and do harm to organ health. This panel studies over 130 genes across a broad immunological disease and syndrome spectrum, including some common diseases like rheumatoid arthritis, asthma, psoriasis, flu, inflammatory bowel disease, etc.

Show More Information →
DISEASE LIST (9)
  • Autoimmune lymphoproferative syndrome
  • Immunodeficiency
  • Mendelian susceptibility to mycobacterial disease
  • Systemic lupus erythematosus
  • Rheumatoid arthritis
  • Psoriasis
  • Asthma
  • Flu
  • Early onset inflammatory bowel disease
GENE LIST (130+)

ADA, ADRB2, AICDA, AIRE, AK2, ALOX5, BANK1, BLM, BTK, C!QA, C1QB, C1QC, C2, C3, CARD14, CASP10, CASP8, CCL11, CD19, CD244, CD247, CD3D, CD3E, CD3Z, CD40, CD40LG, CIITA, CR2, CSF1R, CTLA4, CYBA, CYBB, DCLRE1C, DNASE1, DNASE1L3, DNMT3B, DOCK8, DPP10, ELANE, F12, FAS, FASLG, FCGR2B, FOXN1, FOXP3, GATA2, HLA-C, HLA-DRB1, HNMT, HPS1, HPS4, HPS6, ICOS, IFITM3, IFNGR1, IL10, IL10RA, IL12B, IL12RB1, IL13, IL17F, IL17RA, IL2RA, IL2RG, IL36RN, IL7R, IRAK4, IRF5, ITGAM, ITGB2, ITK, JAK3, LIG4, LRBA, LTA, MEFV, MVK, NCF1, NCF2, NCF4, NFKBIA, NFKBIL1, NHEJ1, NLRP3, NOD2, NRAS, ORAI1, PADI4, PHF11, PLA2G7, PNP, PRF1, PTEN, PTPN22, PTPRC, RAC2, RAG1, RAG2, RET, RFX5, RFXANK, RFXAP, RMRP, SAMHD1, SCGB1A1, SCGB3A2, SERPING1, SH2D1A, SLC22A4, SLC37A4, SLEB13, SLEB3, SLEB7, SP110, SPINK5, STAT1, STAT3, STAT4, STAT5B, STIM1, STXBP2, TBX1, TLR5, TNF, TNFRSF13B, TNFRSF13C, TRAF3IP2, TREX1, TTC37, UNC119, UNC13D, UNG, UPB1, WAS, XIAP, ZAP70

Endocirinological

Endocrine and Metabolic Syndromes

The endocrine and metabolic systems are the body's power plant and manage the way the body produces energy. Metabolic syndrome is the name for a group of risk factors that raises your risk for heart disease and other health problems. The endocrine system is a network of glands that produce and release hormones that help control many important body functions, including the body's ability to change calories into energy that powers cells and organs. The most commonly known disorders in this group are diabetes and obesity. It also explores other lesser noticed endocrine conditions like growth hormone deficiency, which plays a pivotal role in childhood growth and development. This group studies more than 270 genes involving human hormone and metabolic regulation.

Show More Information →
DISEASE LIST (9)
  • Diabetes
  • Growth hormone deficiency
  • Hypogonadotropic hypogonadism
  • Obesity
  • Hemochromatosis
  • Glycogen storage disorders
  • Lysosomal storage disorders
  • Pyruvate dehydrogenase deficiency
  • Peroxisomal disorders
GENE LIST (270+)

ABCC8, ABCD1, ACAD8, ACAD9, ACADM, ACADVL, ACAT1, ACE, ACOX1, ADIPOQ, AGA, AGL, AGPS, AGRP, AKT2, ALB, ALDH4A1, ALDOA, ALG12, ALG2, ALG3, ALG6, ALG8, ALG9, AMACR, AMPD3, AP3B1, AQP2, ARSA, ARSB, ASL, ASS1, ATP13A2, ATP6V0A2, B4GALT1, BLK, BLOC1S3, BTD, BTK, CARTPT, CBS, CEL, CHD7, CISD2, CLN3, CLN5, CLN6, CLN8, COG1, COG4, COG5, COG7, COG8, CP, CPT1A, CPT2, CTNS, CTSA, CTSD, CUL3, CYP11A1, DBH, DICER1, DLD, DNAJC5, DOLK, DPAGT1, DPM1, DTNBP1, EIF2AK3, ENO3, ENPP1, ETFA, ETFB, ETFDH, FAH, FBP1, FGFR1, FH, FOXE1, FOXP3, FSHB, FTCD, FTH1, FTO, FUCA1, G6PC, G6PD, GAA, GALC, GALE, GALK1, GALNS, GALT, GATA4, GATA6, GBA, GBE1, GCDH, GCK, GCM2, GH1, GHR, GHRL, GLA, GLB1, GLIS3, GLUD1, GM2A, GNE, GNPTAB, GNPTG, GNRH1, GNRHR, GNS, GRN, GUSB, GYG1, GYS1, GYS2, HADH, HADHA, HADHB, HAMP, HESX1, HEXA, HEXB, HFE, HFE2, HGSNAT, HLCS, HMGCL, HNF1A, HNF1B, HNF4A, HPS1, HPS3, HPS4, HPS5, HPS6, HSD17B4, HYAL1, IDS, IDUA, IER3IP1, IL1RN, IL2RA, INS, INSR, IVD, IYD, KCNJ11, KCNQ1, KHK, KL, KLF11, LAMP2, LDHA, LEPR, LHX3, LHX4, LIPA, MAN2B1, MANBA, MC2R, MC4R, MCCC2, MFSD8, MGAT2, MLYCD, MMAA, MMAB, MMACHC, MNX1, MOCS1, MOGS, MPDU1, MPI, MRAP, MUT, NAGA, NAGLU, NEU1, NEUROD1, NEUROG3, NKX2-2, NPC1, NPC2, NR3C1, OTC, OTX2, OXCT1, PAH, PAX4, PAX8, PCCA, PCCB, PCK1, PCK2, PCSK1, PDP1, PDX1, PEX1, PEX10, PEX12, PEX13, PEX14, PEX16, PEX19, PEX2, PEX26, PEX3, PEX5, PEX6, PEX7, PFKM, PGAM2, PGM1, PHKA1, PHKA2, PHKB, PHKG2, PHYH, PMM2, PNPLA2, POLR3A, POMC, POU1F1, PPARG, PPARGC1B, PPOX, PPT1, PRKAG2, PROKR2, PSAP, PTF1A, PTH, PYGL, PYGM, RFT1, RFX6, SDC3, SGSH, SI, SLC17A5, SLC22A5, SLC25A20, SLC2A2, SLC35A1, SLC35C1, SLC37A4, SLC3A1, SLC40A1, SMPD1, SOD2, STAT5B, STX16, SUMF1, SUOX, TACR3, TBX19, TCF7L2, TFR2, THRB, TPP1, TUSC3, UPB1, UROD, VKORC1, WFS1, WNK1, WNK4, ZFP57

Neuro

Neurological disorders

Neurological disorders are diseases of the nervous system including the brain, spinal cord, cranial nerves, peripheral nerves, nerve roots, autonomic nervous system, neuromuscular junction, and muscles. Some diseases like Alzheimer's have a strong genetic component and can manifest themselves earlier in life. While there may not be a cure, lifestyle changes can play a significant role in reducing risk. In addition, this panel also enables investigation on some even more common conditions like migraine and Mendelian neurological syndromes. This grouping examines over 450 genes for 17 common cognitive and neuromuscular diseases involving central and peripheral nervous systems. Well-known neurological diseases like autism, Alzheimer's, Parkinson's, dementia, intellectual disability, and hearing loss are studied. Genes underlying neuromuscular diseases like ataxia, dystonia, and amyotrophic lateral sclerosis, myasthenic syndrome are also investigated.

Show More Information →
DISEASE LIST (16)
  • Alzheimer's disease
  • Parkinson's disease
  • Dementia
  • Autism
  • Epilepsy
  • Migraine
  • Hearing loss
  • Dystonia
  • Spinal muscular atrophy
  • Periodic paralysis hypokalemic
  • Myasthenic syndrome
  • Amyotrophic lateral sclerosis
  • Charcot-Marie-Tooth disease
  • Spastic paraplegia
  • Intellectual disability
  • Ischemic stroke
GENE LIST (480+)

A2M, AARS, ABAT, ABCB7, ACE, ACTA2, ADSL, AFG3L2, ALDH4A1, ALDH5A1, ALDH7A1, ALS2, ANG, ANKRD11, ANO10, ANO5, AP1S2, AP1S2, APOE, APP, AR, ARHGEF6, ARHGEF9, ARSA, ARX, ARX, ASAH1, ASPM, ATL1, ATP13A2, ATP1A2, ATP1A3, ATP6AP2, ATRX, ATRX, AUTS2, AVPR1A, BCK, BCKDK, BDNF, BRAF, BSCL2, C18orf1, C19orf12, C5orf42, CACNA1C, CACNA1E, CACNA1S, CACNB4, CALHM1, CAPN3, CASK, CASK, CASR, CAV3, CCT5, CD33, CDKL5, CDKL5, CENPJ, CHD7, CHD8, CHMP2B, CHRNA1, CHRNA2, CHRNA4, CHRNA7, CHRNB1, CHRNB2, CHRND, CHRNE, CLDN14, CLN3, CLN5, CLN6, CLN8, CLU, CNTNAP2, CNTNAP2, CNTNAP5, COCH, COL4A1, COLQ, CPA6, CR1, CREBBP, CSF1R, CSTB, CTSD, CUL4B, CYP27A1, CYP7B1, DAG1, DCTN1, DCX, DES, DFNA5, DFNB59, DHCR7, DIAPH1, DLAT, DLGAP2, DNAJB6, DNAJC5, DNM1L, DNM2, DNMT1, DOCK4, DOCK8, DPAGT1, DPP10, DPP6, DRD2, DST, DYNC1H1, DYSF, EDNRA, EFHC1, EGR2, EHMT1, EMD, EMX2, EPM2A, ESR1, ESRRB, EZH2, F2, F5, FA2H, FAM134B, FBX07, FGD1, FGD4, FGF14, FHL1, FIG4, FKRP, FKTN, FLNA, FOLR1, FOLR1, FOXG1, FOXG1, FOXP1, FOXP2, FUS, GABRA1, GABRA2, GABRB3, GABRG1, GABRG2, GAMT, GARS, GATM, GBA, GCDH, GCH1, GDAP1, GFPT1, GJB1, GJB2, GJB3, GLI3, GNA14, GNRHR, GOSR2, GPC3, GPR56, GPR98, GRIN2A, GRIN2B, GRIN2B, GRN, GRPR, GRXCR1, GSTO1, GSTO2, HCN1, HCN4, HGF, HOXA1, HOXA2, HPRT1, HSD17B10, HSPB1, HSPB8, HSPD1, HTR1B, HTR3A, HTRA2, IDS, IL1RAPL1, IMMP2L, ISPD, ITPR1, KANSL1, KARS, KATNAL2, KCNA1, KCNJ10, KCNJ11, KCNJ18, KCNK18, KCNK9, KCNMA1, KCNQ2, KCNQ3, KCNT1, KCTD13, KCTD7, KDM5C, KDM5C, KIAA0196, KIF1A, KIF1B, KIF5A, KIRREL3, KIRREL3, KLHL3, L1CAM, LAMA2, LAMC3, LGI1, LHFPL5, LIAS, LITAF, LMNA, LOXHD1, LRRK2, LRSAM1, LRTOMT, MAGI2, MAN1B1, MAPT, MARVELD2, MBD5, MBD5, MCPH1, MECP2, MECP2, MED12, MED12, MED25, MEF2C, MEF2C, MET, MFN2, MFSD8, MID1, MIR96, MPZ, MTHFR, MTMR2, MTND1, MTND6, MUSK, MYH14, MYO15A, MYO1A, MYO3A, MYO6, MYOT, NDE1, NDRG1, NDUFA1, NEFL, NEGR1, NFIX, NHLRC1, NHS, NIPA1, NIPBL, NLGN3, NLGN4X, NPC1, NPC2, NRXN1, NRXN1, NSD1, NSD1, NSUN2, NTNG1, OPA1, OPHN1, OPHN1, OPTN, OTOF, PAFAH1B1, PAFAH1B1, PANK2, PARK2, PARK5, PARK7, PAX3, PCDH19, PCDH19, PCDH9, PDE10A, PDE8B, PDGFRB, PDSS1, PDYN, PEX11B, PHF6, PHF6, PICALM, PIGL, PIGV, PINK1, PIP5K1B, PLA2G6, PLCB1, PLEC, PLEKHG5, PMP22, PNKD, PNKP, PNPLA6, PNPO, POLG, POLR3A, POLR3B, POMGNT1, POMT1, POMT2, PON3, POU3F4, POU4F3, PPT1, PQBP1, PRICKLE1, PRICKLE2, PRKCG, PRKRA, PRNP, PRPS1, PRRT2, PRX, PSEN1, PSEN2, PTCH1, PTCHD1, PTEN, PTEN, PTPN11, RAB39B, RAB39B, RAB7A, RAI1, RAPSN, RBFOX1, RDX, RELN, RNASEH2A, RPL10, SATB2, SBF2, SCARB2, SCN1A, SCN1A, SCN1B, SCN2A, SCN2A, SCN3A, SCN4A, SCN8A, SCN9A, SERPINI1, SETX, SGCA, SGCB, SGCD, SGCE, SGCG, SH3TC2, SHANK2, SHANK3, SHH, SIX1, SIX3, SLC17A8, SLC19A3, SLC1A3, SLC20A2, SLC25A19, SLC25A22, SLC26A5, SLC2A1, SLC33A1, SLC6A3, SLC6A4, SLC9A6, SLC9A6, SLC9A9, SMARCA2, SMARCA4, SMARCB1, SMC1A, SMG6, SMPX, SNAI2, SNCA, SNCAIP, SNRPN, SOD1, SORL1, SOX10, SOX5, SPAST, SPAST, SPG11, SPG7, SPR, SPTAN1, SPTBN2, SPTLC2, SRPX2, ST3GAL3, ST3GAL5, ST7, STIL, STK3, STXBP1, SUOX, SYN1, SYNE1, TAF1, TARDBP, TBC1D24, TCAP, TCF4, TCF4, TDP1, TECTA, TGM6, TH, THAP1, TMC1, TMIE, TMPRSS3, TNF, TOMM40, TOR1A, TPP1, TRAPPC9, TREM2, TRIM32, TRPV4, TSC1, TSC1, TSC2, TSC2, TSEN54, TTN, TTR, TUSC3, TYROBP, UBA1, UBE3A, UBE3A, UCHL1, UPF3B, VAPB, VCP, VLDLR, VPS13B, VPS35, VRK1, WDR62, WFS1, YARS, ZEB2, ZEB2, ZFYVE26, ZFYVE27, ZNF507, ZNF804A, ZNF81, ZNHIT6

Mental Disorders

Mental disorders

A mental disorder is a condition that impacts a person's thinking, feeling, or mood and behavior. It may affect the ability to relate to others and function on a daily basis. Genetics, environment, and lifestyle combine to influence whether someone develops a mental disorder. This group studies 23 susceptibility genes associated with psychiatric conditions. Examples of mental disorders include depression, anxiety disorders, schizophrenia, eating disorders, and addictive behaviors.

Show More Information →
DISEASE LIST (N/A)
  • Schizophrenia
  • Stress, anxiety, depression
GENE LIST (23)

BNDF, COMT, DAO, DAOA, DBH, DISC1, DISC2, DRD2, DRD3, DRD4, DTNBP1, HTR1A, HTR1B, HTR2A, MAOA, MTHFR, SHANK3, SLC1A1, SLC6A4, SYN2, TPH1, TSPO, TTF2

Microbial

Mitochondrial diseases

Mitochondrial diseases are a group of disorders caused by failures of the mitochondria, specialized organelles present in every cell of the body except red blood cells. Mitochondria are the powerhouses inside of cells, creating more than 90% of the energy needed by the body to sustain life and support growth. Mitochondrial diseases are inherited chronic diseases that can be present at birth or develop later in life. Symptoms might include poor growth, developmental delays, and muscle weakness. This group studies more than 460 susceptibility genes associated with mitochondrial diseases, such as mitochondrial myopathy and Leigh syndrome.

Show More Information →
DISEASE LIST (N/A)
  • Mitochondrial diseases (nuclear, comprehensive)
GENE LIST (460+)

AARS2, AASS, ABAT, ABCB6, ABCB7, ABCD1, ABHD5, ACAD8, ACAD9, ACADL, ACADM, ACADS, ACADSB, ACADVL, ACAT1, ACO2, ACSF3, ACSL4, ADCK3, AFG3L2, AGK, AGXT, AIFM1, AIFM2, AK2, AKR1D1, ALAS2, ALDH18A1, ALDH2, ALDH4A1, ALDH5A1, ALDH6A1, ALG1, ALG12, ALG2, ALG3, ALG6, ALG8, ALG9, AMACR, AMT, APEX2, APTX, ARG1, ARMS2, ASL, ASS1, ATL1, ATM, ATP5A1, ATP5B, ATP5C1, ATP5D, ATP5E, ATP5F1, ATP5G1, ATP5G2, ATP5G3, ATP5I, ATP5J, ATP5O, ATP7B, ATPAF1, ATPAF2, ATPIF1, ATXN10, ATXN7, AUH, B4GALT1, BCKDHA, BCKDHB, BCL2, BCS1L, BRAF, BRIP1, BTD, C10orf2, C12orf65, C14orf2, CAPN3, CARS2, CAV3, CDKL5, CHKB, CISD2, CLN3, CLN5, CLN6, CLN8, CMC1, COG1, COG7, COG8, COQ2, COQ3, COQ4, COQ6, COQ7, COQ9, COX10, COX11, COX15, COX17, COX18, COX19, COX4I1, COX4I2, COX5A, COX5B, COX6A1, COX6A2, COX6B1, COX6C, COX7A1, COX7A2, COX7A2L, COX7B, COX7B2, COX7C, COX8A, CPOX, CPS1, CPT1A, CPT2, CRBN, CRLS1, CRYAB, CTNS, CTSD, CYB5A, CYB5R3, CYBA, CYBB, CYC1, CYCS, CYP11A1, CYP11B1, CYP11B2, CYP24A1, CYP27A1, CYP27B1, CYP7B1, D2HGDH, DARS2, DBT, DCX, DECR1, DGUOK, DHODH, DIABLO, DLAT, DLD, DLST, DMGDH, DMPK, DNAJC19, DNM1L, DNM2, DOLK, DPAGT1, DPM1, DPM3, EARS2, ECSIT, EIF2AK3, ELOVL4, ETFA, ETFB, ETFDH, ETHE1, FA2H, FARS2, FASTKD2, FECH, FGF14, FH, FOXG1, FOXRED1, FXN, GAA, GAD1, GAMT, GARS, GATM, GCDH, GCK, GCSH, GDAP1, GFER, GFM1, GK, GLA, GLDC, GLRX5, GLUD1, GNPAT, GPD2, GPHN, GSR, HADH, HADHA, HADHB, HARS2, HAX1, HCCS, HFE, HK1, HLCS, HMGCL, HMGCS2, HSD17B10, HSD3B2, HSPA9, HSPD1, HTRA2, IARS2, IDH2, IDH3B, ISCU, ITPR1, IVD, KARS, KCNC3, KCNJ11, KIAA0196, KIAA0226, KIF1B, KIF5A, LARS2, LETM1, LIAS, LMBRD1, LRPPRC, MAOA, MAPT, MARS2, MCCC1, MCCC2, MCEE, ME2, MECP2, MFN2, MFSD8, MGAT2, MIP, MLYCD, MMAA, MMAB, MMACHC, MMADHC, MOCS1, MOCS2, MOGS, MPDU1, MPI, MPV17, MRPL3, MRPS16, MRPS22, MTFMT, MTHFD1, MTO1, MTPAP, MTRR, MUT, MUTYH, MYH7, NAGS, NARS2, NDUFA1, NDUFA10, NDUFA11, NDUFA12, NDUFA13, NDUFA2, NDUFA3, NDUFA4, NDUFA5, NDUFA6, NDUFA7, NDUFA8, NDUFA9, NDUFAB1, NDUFAF1, NDUFAF2, NDUFAF3, NDUFAF4, NDUFAF5, NDUFAF6, NDUFB1, NDUFB10, NDUFB11, NDUFB2, NDUFB3, NDUFB4, NDUFB5, NDUFB6, NDUFB7, NDUFB8, NDUFB9, NDUFC1, NDUFC2, NDUFS1, NDUFS2, NDUFS3, NDUFS4, NDUFS5, NDUFS6, NDUFS7, NDUFS8, NDUFV1, NDUFV2, NDUFV3, NEFL, NIPA1, NKX2-1, NPC1, NPC2, NUBPL, OAT, OGDH, OGG1, OPA1, OPA3, OTC, OXA1L, OXCT1, PAFAH1B1, PANK2, PARK7, PARL, PARS2, PC, PCCA, PCCB, PCK2, PDHA1, PDHB, PDHX, PDP1, PDSS1, PDSS2, PDX1, PEX13, PHB, PHYH, PINK1, PLP1, PMM2, PNKD, PNPLA2, PNPLA3, POLG, POLG2, PPM1B, PPOX, PPT1, PREPL, PRKCG, PRODH, PTRF, PUS1, PWAR1, RARS2, REEP1, RFT1, RMRP, RNASEH2A, RNASEH2B, RNASEH2C, RNASEL, RRM2B, RYR1, SAMHD1, SARDH, SARS2, SCN1A, SCO1, SCO2, SCP2, SDHA, SDHAF1, SDHAF2, SDHB, SDHC, SDHD, SGCD, SLC12A3, SLC16A2, SLC19A2, SLC22A5, SLC25A12, SLC25A13, SLC25A15, SLC25A16, SLC25A19, SLC25A20, SLC25A22, SLC25A3, SLC25A38, SLC25A4, SLC29A3, SLC2A1, SLC2A10, SLC33A1, SLC35A1, SLC35C1, SLC3A1, SLC52A1, SLC6A8, SLC7A9, SLC9A6, SOD1, SOD2, SPAST, SPG11, SPG20, SPG7, SPTBN2, STAR, SUCLA2, SUCLG1, SUGCT, SUOX, SURF1, TACO1, TARS2, TAZ, TIMM44, TIMM8A, TK2, TMEM126A, TMEM70, TMLHE, TOP1MT, TPM2, TPP1, TRMU, TSFM, TTBK2, TUFM, TYMP, UBE3A, UCP1, UCP2, UCP3, UNG, UQCR10, UQCR11, UQCRB, UQCRC1, UQCRC2, UQCRFS1, UQCRH, UQCRQ, UROS, USMG5, VARS2, WARS2, WFS1, XDH, XPNPEP3, YARS2, ZFYVE26

Organ Health

Organ Health

This grouping covers specific diseases and syndromes involving lung, bone, kidney, liver, eye, nose, throat, blood, skin, hair, and teeth. Some common disease conditions like osteoporosis (low bone density), anemia, cataracts, red-green color blindness, and alopecia (loss of hair) are included. Diseases of 11 organs and over 740 organ health-related genes are studied.

Show More Information →
DISEASE LIST (31)
  • Cystic lung
  • Bronchiectasis
  • Pulmonary fibrosis
  • Short stature
  • Skeleton malformation
  • Osteogenesis imperfecta
  • Skeletal dysplasia
  • Kidney diseases
  • Diarrhea
  • Cholestasis
  • Hemochromatosis
  • Congenital hepatic fibrosis
  • Cataract
  • Glaucoma
  • Night vision deficiency
  • Macular degeneration
  • Achromatopsia
  • Red-green color vision defect
  • Bleeding disorder
  • Fanconi anemia
  • Hemolytic anemia
  • Diamond-Blackfan anemia
  • Aplastic anemia
  • Congenital dyserythropoietic anemia
  • Hemolytic uremic syndrome atypical
  • Alpha thalassemia
  • Ichthyosis
  • Albinism
  • Xeroderma pigmentosum
  • Alopecia
  • Tooth
GENE LIST (750+)

ABCA12, ABCA3, ABCA4, ABCB11, ABCB4, ABCB7, ABCC2, ABCG5, ABCG8, ABHD5, ACAN, ACE, ACP5, ACTN4, ACVR1, ADA, ADAMTS13, ADAR, AGL, AGT, AGTR1, AHI1, AIPL1, AK1, AKR1D1, ALB, ALDH18A1, ALDH3A2, ALDOA, ALMS1, ALOX12B, ALOXE3, ALPL, ALX4, ANK1, ANKH, ANO5, ANO6, ANTXR2, AP1S1, AP3B1, APLN, APOC3, APOL1, AQP2, ARHGAP31, ARL13B, ARL6, ARMS2, ARSE, ATP2A2, ATP2C1, ATP6V0A2, ATP6V0A4, ATP6V1B1, ATP8B1, ATR, AVP, AVPR2, B3GALT6, B4GALT7, B9D1, B9D2, BAAT, BACH1, BBS1, BBS10, BBS12, BBS2, BBS4, BBS5, BBS7, BBS9, BCOR, BEST1, BFSP2, BICC1, BLOC1S1, BLOC1S3, BLOC1S6, BMP2, BMP4, BMPER, BMPR1B, BRCA2, BRIP1, BSND, BTD, C15ORF41, C1QA, C1QB, C1QC, C1QTNF5, C2orf71, C3, C5ORF42, CA2, CA4, CABP4, CACNA2D4, CANT1, CASR, CC2D2A, CCDC28B, CCDC39, CCDC40, CD151, CD2AP, CD46, CDAN1, CDC73, CDH23, CDH3, CDKN1C, CEP290, CEP41, CERS3, CFB, CFH, CFHR1, CFHR3, CFHR5, CFI, CFTR, CHD1L, CHM, CHN1, CHST13, CHST14, CHST3, CHST6, CHSY1, CLCN5, CLCN7, CLCNKA, CLCNKB, CLDN1, CLDN16, CLRN1, CNGA3, CNGB1, CNGB3, COL10A1, COL11A1, COL11A2, COL17A1, COL1A1, COL1A2, COL2A1, COL4A3, COL4A4, COL4A5, COL9A1, COL9A2, COL9A3, COMP, CPT2, CRB1, CRTAP, CRX, CRYAA, CRYBB1, CSF1, CSF2RA, CTNS, CTSK, CUBN, CUL3, CUL7, CYCS, CYLD, CYP1B1, CYP24A1, CYP27A1, CYP4F22, CYP7A1, CYP7B1, DCAF17, DCDC1, DDB2, DDR2, DFNB31, DGUOK, DHCR24, DHCR7, DKC1, DLAT, DLL3, DLX3, DMP1, DNAAF1, DNAAF2, DNAH11, DNAH5, DNAI1, DNAI2, DNAL1, DSG4, DTNBP1, DYM, DYNC2H1, EBP, EDARADD, EFEMP2, EGLN1, EIF2AK3, ELANE, ELMOD2, ELN, ELOVL4, ELP4, ENAM, ENO3, ENPP1, EPAS1, EPB41, EPB42, EPHA2, EPOR, ERCC1, ERCC2, ERCC3, ERCC4, ERCC5, ERCC8, ESCO2, EVC, EVC2, EXT1, EXT2, EYA1, EYS, F10, F11, F12, F13A1, F13B, F2, F5, F7, F8, F9, FAH, FAM161A, FAM20C, FANCA, FANCB, FANCC, FANCD2, FANCE, FANCF, FANCG, FANCI, FANCL, FANCM, FBLN1, FBLN5, FBN1, FBP1, FBXW4, FERMT1, FERMT3, FGA, FGB, FGF10, FGF23, FGF9, FGFR1, FGFR2, FGFR3, FGG, FH, FKBP10, FLCN, FLNA, FLNB, FMN1, FOXC1, FOXF1, FOXN1, FRMD7, FTH1, FTL, FYCO1, FZD4, G6PC, G6PC3, G6PD, GAA, GALNT3, GATA1, GATA3, GBE1, GCLC, GDF5, GDF6, GDNF, GFI1, GGCX, GH1, GHSR, GJA3, GJA8, GJB2, GJB3, GJB4, GJB6, GLI3, GLIS2, GLMN, GNAS, GNAT1, GNAT2, GORAB, GP1BA, GP1BB, GP6, GP9, GPC6, GPI, GPR143, GPR179, GPR98, GPX1, GREM1, GRHPR, GRK1, GSR, GSS, GUCA1B, GUCY2D, GYG1, GYS1, GYS2, HAMP, HBB, HDAC4, HESX1, HFE, HFE2, HK1, HMCN1, HMGCS2, HNF1B, HOGA1, HOXD13, HPGD, HPS1, HPS3, HPS4, HPS5, HPS6, HR, HSD11B2, HSD3B7, HSPG2, ICK, IFITM5, IFNG, IFT122, IFT140, IFT80, IHH, IL36RN, IMPAD1, IMPDH1, IMPG2, INF2, INVS, IQCB1, ITGA2, ITGA2B, ITGB3, JAG1, JAK2, KCNJ1, KIF21A, KIF22, KIF23, KIF7, KLF1, KLHL3, KLHL7, KRT1, KRT10, KRT2, KRT5, KRT83, KRT9, LAMB2, LAMP2, LBR, LDHA, LEMD3, LIFR, LIM2, LIPA, LIPN, LMAN1, LMBR1, LMNA, LMX1B, LOR, LRAT, LRP2, LRP4, LRP5, LTBP2, LTBP4, LZTFL1, MAFB, MAK, MARS, MASTL, MATN3, MCFD2, MEFV, MERTK, MGP, MKKS, MKS1, MMP13, MMP2, MMP20, MMP9, MPL, MPV17, MSX2, MTAP, MUC5B, MYBPC1, MYCN, MYH9, MYO1E, MYO7A, MYOC, NBEAL2, NBN, NDP, NEK1, NEK8, NHP2, NIPAL4, NIPBL, NKX2-1, NKX3-2, NME8, NOG, NOP10, NOTCH2, NPC1, NPC2, NPHP1, NPHP3, NPHP4, NPHS1, NPHS2, NPR2, NR1H4, NR2E3, NR3C2, NRL, NT5C3A, NYX, OBSL1, OCA2, OCRL, OFD1, OPA1, OPN1LW, OPN1MW, OPTN, OSTM1, P3H1, PALB2, PAPSS2, PAX2, PAX6, PAX9, PCDH15, PCK1, PCK2, PCNT, PDE6A, PDE6B, PDE6C, PDE6G, PDE6H, PEX1, PEX10, PEX11B, PEX12, PEX13, PEX14, PEX16, PEX19, PEX2, PEX26, PEX3, PEX5, PEX6, PEX7, PFKM, PGAM2, PGK1, PGM1, PHEX, PHKA1, PHKA2, PHKB, PHKG2, PHYH, PIEZO1, PIGV, PIKFYVE, PITX1, PITX2, PKD1, PKD2, PKDH1, PKHD1, PKLR, PLAU, PLCB4, PLCE1, PLOD2, PNPLA1, POLG, POLH, POLR1D, POMP, PPIB, PRCD, PRDM5, PRKAG2, PRKAR1A, PRKCSH, PROM1, PROS1, PRPF3, PRPF31, PRPF6, PRPF8, PTH1R, PTHLH, PTPN11, PTPRO, PYCR1, PYGL, PYGM, RAD51C, RASGRP2, RAX2, RBP3, RDH5, RDS, RECQL4, REN, RET, RHAG, RHO, RLBP1, RMRP, ROBO2, ROR2, RP1, RP1L1, RP2, RPE65, RPGRIP1, RPGRIP1L, RPL11, RPL19, RPL26, RPL35A, RPL5, RPS10, RPS17, RPS19, RPS24, RPS26, RPS7, RSPH4A, RSPH9, RTEL1, RUNX2, SAG, SALL4, SARS2, SBDS, SCNN1A, SCNN1B, SCNN1G, SDCCAG8, SEC23B, SEC63, SEMA4A, SERPINA1, SERPINE1, SERPINF1, SERPINF2, SERPING1, SERPINH1, SF3B4, SFTPA1, SFTPA2, SFTPB, SFTPC, SFTPD, SH2D1A, SH3BP2, SH3PXD2B, SHH, SHOX, SIX1, SIX5, SIX6, SLC11A2, SLC12A1, SLC12A3, SLC24A1, SLC25A13, SLC25A38, SLC25A4, SLC26A2, SLC27A4, SLC27A5, SLC2A1, SLC2A2, SLC2A9, SLC34A1, SLC34A3, SLC35D1, SLC37A4, SLC39A4, SLC40A1, SLC45A2, SLC4A1, SLC4A4, SLCO1B3, SLURP1, SLX4, SMARCAL1, SMPD1, SNAP29, SNRNP200, SOST, SOX17, SOX9, SP110, SP7, SPATA7, SPINK5, SPTA1, SPTB, SQSTM1, SRP72, ST14, STS, SULF1, TBCE, TBX15, TBX3, TBX4, TBX5, TBXA2R, TBXAS1, TCIRG1, TCN2, TCTN1, TCTN2, TCTN3, TDRD7, TEME67, TERC, TERT, TF, TFR2, TGM1, TGM5, THBD, THPO, TINF2, TJP2, TMEM216, TMEM237, TMEM67, TMPRSS6, TNFRSF11A, TNFRSF11B, TNFSF11, TNNI2, TNNT3, TOPORS, TP63, TPI1, TREM2, TRIM32, TRIP11, TRMU, TRPC6, TRPM1, TRPS1, TRPV3, TRPV4, TSC1, TSC2, TSHZ1, TTC21B, TTC8, TULP1, TYR, TYROBP, TYRP1, UGT1A1, UGT1A7, UMOD, UNC119, UPK3A, USH1C, USH1G, USH2A, VHL, VIPAS39, VPS33B, VSX2, VWF, WAS, WDPCP, WDR19, WDR35, WDR36, WDR72, WNK1, WNK4, WNT3, WNT5A, WNT7A, WRAP53, WT1, XK, XLRS1, XPA, XPC, XPNPEP3, ZMPSTE24, ZNF469, ZNF513

Reproductive

Reproductive Health and Family Planning

Genetics bond families together. Close family members share up to 50% of their DNA. Genetic mutations can impact families through inherited conditions or with family planning. Carrier Screening explores genetic variants that may influence and inform decisions about having children and their potential long-term medical needs. Newborn screening identifies conditions that can affect a child's long-term health or survival. Early detection, diagnosis, and intervention can prevent death or disability and help children reach their full potential. The panel covers carrier screening, fertility screening, newborn screening, and recurrent miscarriage. More than 340 genes are studied.

Show More Information →
DISEASE LIST (N/A)
  • Carrier
  • Newborn
  • Fertility
  • Recurrent miscarriage
GENE LIST (340+)

Carrier, AAAS, ABCA4, ABCB11, ABCC6, ABCC8, ABCD1, ACADM, ACADS, ACADSB, ACADVL, ACAT1, ACOX1, ADA, ADAMTS2, AGA, AGL, AGXT, AIRE, ALDH3A2 , ALDH7A1, ALDOB, ALG6, ALPL, AMH, AMHR2, AMT, AR, ARSA, ARSB, ASL, ASPA, ASS1, ATM, ATP7A, ATP7B, AVP, BBS1, BBS10, BBS11, BBS12, BBS2, BCHE, BCKDHA, BCKDHB, BCS1L, BLM, BRIP1, BSND, BTD, CAPN3, CBS, CDH23, CEP290, CFTR, CHM, CHRNE, CHRNG, CIITA, CLN3, CLN5, CLN6, CLN8, CLRN1, CNGB3, COL4A3, COL4A4, COL4A5, COL7A1, CPT1A, CPT2, CRB1, CTNS, CTSC, CTSK, CYBB, CYP1B1, CYP11B1, CYP11B2, CYP17A1, CYP19A1, CYP1B1, CYP21A2, CYP27A1, CYP27B1, DBT, DCLRE1C, DFNB3, DHCR7, DHDDS, DLD, DMD, DNAH5, DNAI1, DPYD, EDA, EDAR, EIF2B5, EMD, ETFA, ETFDH, ETHE1, EVC, EVC2, EYS, F11, F2, F5, F8, F9, FAH, FANCA, FANCC, FANCG, FH, FKRP, FKBP10, FKTN, G6PC, G6PD, GAA, GALC, GALK1, GALNS, GALT, GAMT, GBA, GBE1, GCDH, GDF5, GHRHR, GJB1, GJB2, GJB6, GLA, GLB1, GLDC, GNE, GNPTAB, GNS, GP1BA, GP1BB, GP9, GPR56, GRHPR, GSS, GUCY2D, GUSB, HADHA, HAX1, HBA1, HBA2, HBB, HEXA, HEXB, HFE, HFE2 , HGD, HGSNAT, HLCS, HMGCL, HMOX1, HOGA1, HPS1, HPS3, HSD17B3, HSD17B4, HSD3B2, IDS, IDUA, IKBKAP, IL2RG, IVD, KCNJ11, LAMA3, LAMB3, LAMC2, LCA5, LDLR, LDLRAP1, LHCGR, LIFR, LIPH, LPL, LRPPRC, MAN2B1, MCCC1 , MCCC2 , MCOLN1, MECP2, MEFV, MFSD8 , MKS1, MLC1, MMAA, MMAB, MMACHC, MPI, MPL, MPV17, MTHFR, MTM1, MTRR, MUT, MYO7A, NAGLU, NBN, NDRG1, NDUFAF5, NEB, NEU1, NLRP7, NPC1, NPC2, NPHS1, NPHS2, NR2E3, OCA2, OPA3, OTC, PAH, PANK2, PC, PCCA, PCCB, PCDH15, PDHA1, PDHB, PEPD, PEX1, PEX10, PEX2, PEX6, PEX7, PFKM, PHGDH, PKHD1, PMM2, POLG, POMGNT1, POR, PPT1, PROP1, PRPS1, PTS, PYGM, RAB23, RAPSN, RDH12, RLBP1, RMRP, RS1, RTEL1, SACS, SERPINA1, SGCA, SGCB, SGCD, SGCG, SGSH, SLC12A3, SLC12A6, SLC17A5, SLC19A2, SLC1A4, SLC22A5, SLC25A13, SLC25A15, SLC26A2, SLC26A3, SLC26A4, SLC35A3, SLC37A4, SLC39A4, SLC3A1, SLC45A2, SLC4A11, SLC6A8, SLC7A7, SLC7A9, SMPD1, SRD5A2, STAR, SUMF1, TCIRG1, TFR2, TGM1, TH, TMEM216, TPP1, TTC37, TTPA, TYR, UGT1A1, USH1C, USH2A, VPS13B, VPS53, VSP13A, VWF, WISP3, WNT10A, WRN, NewBorn, ABCD1, ACAD8, ACADM, ACADS, ACADSB, ACADVL, ACAT1, ADA, AHCY, ARG1, ASL, ASS1, AUH, BCKDHA, BCKDHB, BTD, CBS, CFTR, CPT1A, CPT2, CYP21A2, DBT, DECR1, DLD, DNAJC19, DUOX2, ETFA, ETFB, ETFDH, FAH, GAA, GALC, GALE, GALK1, GALT, GBA, GCDH, GCH1, GJB2, GJB3, GJB6, GLA, GNMT, HADH, HADHA, HADHB, HBA1, HBA2, HBB, HLCS, HMGCL, HPD, HSD17B10, IDUA, IL2RG, IVD, MAT1A, MCCC1, MCCC2, MCEE, MLYCD, MMAA, MMAB, MMADHC, MTHFR, MTR, MTRR, MUT, NPC1, NPC2, OPA3, PAH, PAX8, PCBD1, PCCA, PCCB, PTS, QDPR, SLC22A5, SLC25A13, SLC25A20, SLC5A5, TAT, TAZ, TG, TPO, TSHB, TSHR, Fertility, AR, AURKC, BMP15, CATSPER1, DHH, FGFR1, FIGLA, FSHR, GNRHR, NOBOX, SPATA16, SYCP3, TACR3, PLK4, Recurrent miscarriage, ANXAS, F2, F5

Pharma

Pharmacogenomics

Genetic variations have been linked to differences in the way different people metabolize certain drugs. Two examples are drug sensitivity or the severity of side effects. Knowing this information can help your doctor better select the best medication or adjust medication dosage. This grouping studies the most frequent clinical pharmacogenomic targets to fulfill this purpose. NOTE: Do not make any changes to your medical treatment as a result of getting your whole genome sequenced without a physician's approval.

Show More Information →
DISEASE LIST (N/A)
  • N/A
GENE LIST (40+)

ABL2, ALK, ASL, ASS1, BCR-ABL, BRAF, CFTR, CPS1, CYP2B6, CYP2C19, CYP2C9, CYP2D6, CYP3A5, del (17p), del (5q), DPYD, EGFR, ERBB2, ESR1, F2, F5, FIP1L1-PDGFRA, G6PD, HLA-A, HLA-B, HLA-DQA1, HLA-DQB1, HPRT1, IFNL3, IL2RA, KIT, KRAS, LDLR, MS4A1, NAGS, NAT1, NAT2, OTC, PDGFRB, PGR, PML-RARA, POLG, PROC, PROS, RYR1, SERPINC1, SLCO1B1, TPMT, UGT1A1

Your DNA could very well be the key to getting more out of life.

Veritas myGenome gives you genetic insights about unique personal traits that, for example, could lead to a better workout, perhaps help you with your diet and the foods you love, or result in a more personalized approach to skin care that is just for you. myGenome specifically examines five categories of lifestyle traits, including athleticism, nutrition, longevity/aging, ancestry, and many other non-clinical characteristics. myGenome includes the following lifestyle traits and genes.

Fitness

Athleticism

Are you born to run like an Olympic champion? The answer could lie in your genes. Athletic characteristics such as height, skeletal structure, muscle fiber types, reflex capabilities, metabolic efficiency, and lung capacity are associated with specific genes and variants and are highly heritable. Veritas’ myGenome examines genes and variants associated with athleticism and could help you customize training strategies, maximize training efficiency, and improve athletic performance based on your personal genomic data.

Show More Information →
TRAIT LIST (9)
  • Endurance vs. power performance
  • Tendon Injury
  • VO2 max response to training/effects of exercise
  • Athletic performance
  • Muscle performance
  • Cardiovascular risk/sports performance
  • Aerobic exercise
  • Exercise endurance
  • Elite endurance
GENES & VARIANT LIST (13)

AGT, LOC101448202/COL5A1, KIF5B, CAMTA1, ADRB2, CKM, MSTN/C2orf88, ACTN3, NOS3, PPARD, NRF1, NRF1, SNAPC1

Dietary

Nutrition

Genetic variants are known to affect food tolerances and nutrient absorption among different ethnic groups and may also influence individual dietary requirements. The rising field of nutritional genomics studies personalized nutritional intake for optimal health and disease prevention on the basis of personal genomic profile. Veritas’ myGenome examines genes and variants associated with nutritional needs and biological responses to diet, could help identify discrepancies between your current diet and your daily nutritional needs, and includes recommendations according to your genetic nutrition response to better manage your nutritional balance and live a healthier life.

Show More Information →
TRAIT LIST (13)
  • Daily Caloric Intake Levels, Daily Carbohydrate Intake Level, Fat Sensitivity
  • Response to Diet
  • Hypertriglyceridemia
  • Eating Behavior and bitter taste
  • Adiponectin Levels
  • Cholesterol level
  • HDL ("Good") Cholesterol Levels
  • LDL ("Bad") Cholesterol Levels
  • Metabolic syndrome
  • Cardioprotective
  • Protection against weight regain
  • Dyslipidemia
  • Type 2 diabetes risk / insulin sensitivity
GENES & VARIANT LIST (18)

APOA2, CELSR2, APOA5, ZPR1, APOB, OR9A4/TAS2R38, PPARG, KNG1, PPARD, NUTF2, LOC102725159/ABCG8, LDLR, ACSL1, LOC102724766, TBL2, ADIPOQ, TIMD4, PPARD

Physio

Longevity/aging

“Who wants to live forever?” is a question that has been asked by ancient Egyptian pharaohs, seekers of immortality elixirs and fountains of youth, and even the rock band Queen. An elixir has proven elusive but we do know genes play a role in longevity based on genomic studies on centenarians-people who live to 100 years of age. In this category, Veritas’ myGenome examines genes and variants associated with aging and longevity. Through proprietary models and algorithms, we combine your chronological age, perceived age, epigenetic clock, and telomere clock to give you the most personalized practical guidance on longevity and aging. Along with the athleticism and nutrition reports, we could help you build the most powerful holistic solution to slow aging and make you look younger and live healthier.

Show More Information →
TRAIT LIST (5)
  • Biological aging
  • Longevity
  • Parkinson's disease
  • Cardioprotective
  • Memory
GENES & VARIANT LIST (12)

ZBTB46, IL6/LOC541472, APOC3, TERT, FOXO3, OBFC1, TSPYL6/ACYP2, MYNN, FAM47E/FAM47E-STBD1, MCCC1, LOC102724766, WWC1

Ancestry

Ancestry

myGenome examines your DNA for insight into your ancestral history. People with similar backgrounds share certain patterns of genetic variation, which is not only interesting but could also provide health-related clues. In this category, we compare your genome with others and provide you a report on your ethnic background that may help you find distant relatives based on shared DNA and can potentially also uncover ancestral insights that may inform your health.

Space Genes

Space Genes

The inhospitable environment of outer space poses extraordinary biological challenges for humans living in space. Genes in this group are of particular relevance to health challenges most commonly experienced by astronauts in Space including the impact of long-term exposure to microgravity, living in an environment with low air pressure and low oxygen levels, extended periods in solitude, and exposure to cosmic radiation.

Non Clinical Trials

Other non-clinical traits

Some non-clinical traits such as hair color and bitter taste perception of broccoli are caused by genetic variants. We examine those non-clinical genetic trait variants for insights into how your body responds to lifestyle stimuli.

Show More Information →
TRAIT LIST (24)
  • Obesity
  • Pain sensitivity
  • Alcohol and substance abuse
  • BMI
  • Finger length ratio
  • Height
  • Smoking behavior/nicotine dependence
  • Menarche
  • Iris patterns
  • Hair color
  • Freckling
  • Hair thickness
  • Eye color
  • Menopause
  • Memory
  • Hair curl
  • Earwax type
  • Protection against weight regain
  • Atopic dermatitis
  • Generalized vitiligo (skin health)
  • Keloid
  • Ulcerative colitis
  • Crohn's disease
  • Ankylosing spondylitis
GENES & VARIANT LIST (42)

GNB3/CDCA3, MIR4761/COMT, NPY, IGF1, LIN28B, HMGA2, CHRNA3, DNAJC27, SEMA3A, HERC2, MC1R, MC1R, TUBB3/MC1R, BNC2, SMOC1, TRAF3IP1, EDAR, LOC105373704, OCA2, UQCC1, CCDC85A, LOC105370627, HERC2, MCM8, WWC1, TCHHL1, ABCC11, ADIPOQ, IL13, C1QTNF6, IL2RA, BPESC1, TYR, RNASET2, IL12B, HCG9, RERE, GZMB, LOC105375015/LOC105379660/LOC105379667, UBASH3A, IL23R, LPP

A lifelong asset in the doctor-patient relationship

Veritas myGenome is a lifelong asset for ongoing care and management of a patient’s health and wellness. Sequencing a patient’s whole genome makes their entire genetic code available to you and your patient for re-examination now and throughout their lifetime. That makes whole genome sequencing the new standard in genetics.

Why whole genome is the new standard

The accessibility of Veritas myGenome ($999) makes whole genome sequencing superior to other genetic tests that examine only a fraction of the genomic space. Only whole genome sequencing makes it possible to look at all of your patient’s DNA for genetic variants that are relevant. Exome sequencing and genotyping cover 1.5% and less than 0.1% of the genomic space, respectively, while whole genome sequencing covers 100% of what can be read using currently available state of the art technologies. It means that whole genome sequencing makes it possible for you to return to your patient’s data for more insight as science progresses or new health needs arise.

Also, the fact that we know that over 90% of clinically important variants lie outside of the gene coding regions means that the whole genome is potentially far more clinically useful.11

PROPORTION OF IMPORTANT VARIANTS

Exome 7%

Whole Genome 100%

Clinical grade

Although intended as a screening test, Veritas myGenome is performed using the highest technical as well as clinical standards. We sequence genomes at industry standard depth of 30X average coverage using an Illumina HiSeq X system. The test is performed in our CLIA laboratory following LDT regulations. Each test is reviewed and released by a physician trained in genetics with experience in Next Generation Sequencing. Pre- and post-test genetic counseling are available through our team of certified and licensed genetic counselors. Additional genetic counseling can be requested at any time for an additional fee.

Interpretation benchmark

With over 10 years of experience sequencing and interpreting whole genomes as a part of the Personal Genome Project at Harvard Medical School, our team has built an automated interpretation tool for investigating clinically significant variants that could easily become the standard. The number of conditions included in our interpretation is constantly updated from public databases and is based on what is currently known to be both clinically relevant and valid. Each variant reported as part of our interpretation of a patient’s genome is curated by our team.

Variants of uncertain significance (VUS)

Variants of uncertain significance (VUS) are reported in a supplemental report. In some cases, VUSs may be worth evaluating further based on a patient’s personal and family history to determine if a VUS may in fact have clinical significance. VUS findings may warrant further confirmatory or diagnostic testing.